Where are “favorite loci of SNPs”? 2006/06/01 Areum Han
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Where are “favorite loci of SNPs”?
I believe the genetic loci for SNPs might be determined following function f.f = p * i
p = population of gene products where a SNP is located
(e.g., number of transcripts, durability of transcripts)
i = impact of a SNP to a host gene and neighbor genes
(e.g., closeness to critical sites such as protein interaction sites)The value of f function should not be too large to be eliminated nor too small to make no difference.
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What are “the most effective/strong SNPs" in view of their category? 2006/06/07 Areum Han---------------------------------------------------------------------------------
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Today, in KOBIC Dr.Hahn from NIH had a talk about the human specific mutations.
He focused on frameshift and nonsense(prem-stop) mutations since he assumed that they
make 'strong' differences on protiens. And I agree with that.
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